Polymorphisms in the Renin-Angiotensin System and eNOS Glu298Asp Genes Are Associated with Increased Risk for Essential Hypertension in a Mexican Population

Table 7

AGTR1 A1166C genotype and allele frequency in patients with essential hypertension and controls.

	Patients; ()	Controls; ()	value	OR (95% CI)
Genotype
A/A,	148 (66.1)	135 (64.9)	0.85	0.98 (0.78–1.49)
A/C,	58 (25.9)	61 (29.3)
C/C,	18 (8.0)	12 (5.8)
Dominant model
A/A vs. A/C+C/C,	148 vs.	135 vs.	0.87	0.97 (0.64–1.47)
Recessive model
C/C vs. A/C+A/A,	18 vs.	12 vs.	0.35	1.43 (0.63–3.24)
Allele frequency
A,	354 (79.0)	331 (79.6)	0.84	1.03 (0.73–1.46)
C,	94 (21.0)	85 (20.4)

Data presented are number and % of patients. CI: confidence interval; odds ratio, .