Research Article

Biochemical Evaluation by Confirmatory Tests after Unilateral Adrenalectomy for Primary Aldosteronism

Table 3

Characteristics of patients before and after Adx.

VariablesBefore AdxAfter Adx value

Number of patients16
Age at Adx (year)
Female/male sex9/7
After Adx evaluation time (month)
Presence of hypokalemia (%)500
SBP (mmHg)0.002
DBP (mmHg)0.032
Medication (defined daily dose)<0.001
eGFR (mL/min/1.73 m2)<0.001
Basal PRA (ng/mL/h)<0.001
Basal PAC (ng/dL)<0.001
Basal ARR<0.001
U-Aldo (μg/day)<0.001
AVS (yes/no)15/1
AVS (yes/no)13/3
Tumor detected by CT (yes/no)12/4
Side for adrenalectomy (left/right)10/6
Histological diagnosis (adenoma/cortical nodule)14/2

Adx: unilateral adrenalectomy; SBP: systolic blood pressure; DBP: diastolic blood pressure; Medication: antihypertensive medication; eGFR: estimated glomerular filtration rate; PRA: plasma renin activity; PAC: plasma aldosterone concentration; ARR: aldosterone-renin ratio; U-Aldo: 24 h urine aldosterone; AVS: adrenal venous sampling; LR: lateralized ratio; CR: contralateral ratio; CT: computed tomography. Data are presented as deviation. The Wilcoxon signed-rank test or Fisher’s exact test is performed. value < 0.05.