Biochemical Evaluation by Confirmatory Tests after Unilateral Adrenalectomy for Primary Aldosteronism

Table 5

Patient characteristics of the biochemical outcome by ARR.

	Variables	Biochemical outcome by ARR		value
		ARR complete	ARR partial/absent
	Number of patients	11 (69%)	5 (31%)
	Age at Adx (year)			0.427
Before Adx	Female/male sex	6/5	3/2	0.635
	Presence of hypokalemia (%)	63	20	0.141
	SBP (mmHg)			0.494
	DBP (mmHg)			0.821
	Medication (defined daily dose)			0.568
	eGFR (mL/min/1.73 m2)			0.428
	Basal PRA (ng/mL/h)			0.642
	Basal PAC (ng/dL)			0.257
	Basal ARR			0.821
	U-Aldo (μg/day)			0.350
	AVS (yes/no)	10/1	5/0	0.688
	AVS (yes/no)	10/1	3/2	0.156
	Tumor detected by CT (yes/no)	8/3	4/1	1.000
	Side for Adx (left/right)	5/6	5/0	0.058
After Adx	Evaluation time after Adx (month)			0.422
	Histological diagnosis (adenoma/cortical nodule)	9/2	5/0	0.458
	Presence of hypokalemia (%)	0	0	1.000
	SBP (mmHg)			0.331
	DBP (mmHg)			0.909
	Medication (defined daily dose)			0.950
	eGFR (mL/min/1.73 m^2)			0.734
	Basal PRA (ng/mL/h)			0.020
	Basal PAC (ng/dL)			0.047
	Basal ARR			0.002
	U-Aldo (μg/day)			0.428

Adx: unilateral adrenalectomy; SBP: systolic blood pressure; DBP: diastolic blood pressure; Medication: antihypertensive medication; eGFR: estimated glomerular filtration rate; PRA: plasma renin activity; PAC: plasma aldosterone concentration; ARR: aldosterone-renin ratio; U-Aldo: 24 h urine aldosterone; AVS: adrenal venous sampling; LR: lateralized ratio; CR: contralateral ratio; CT: computed tomography. Data are presented as deviation. The Wilcoxon signed-rank test or Fisher’s exact test is performed. value < 0.05.