Research Article
Biochemical Evaluation by Confirmatory Tests after Unilateral Adrenalectomy for Primary Aldosteronism
Table 5
Patient characteristics of the biochemical outcome by ARR.
| | Variables | Biochemical outcome by ARR | value | ARR complete | ARR partial/absent |
| | Number of patients | 11 (69%) | 5 (31%) | | Age at Adx (year) | | | 0.427 |
| Before Adx | Female/male sex | 6/5 | 3/2 | 0.635 | Presence of hypokalemia (%) | 63 | 20 | 0.141 | SBP (mmHg) | | | 0.494 | DBP (mmHg) | | | 0.821 | Medication (defined daily dose) | | | 0.568 | eGFR (mL/min/1.73 m2) | | | 0.428 | Basal PRA (ng/mL/h) | | | 0.642 | Basal PAC (ng/dL) | | | 0.257 | Basal ARR | | | 0.821 | U-Aldo (μg/day) | | | 0.350 | AVS (yes/no) | 10/1 | 5/0 | 0.688 | AVS (yes/no) | 10/1 | 3/2 | 0.156 | Tumor detected by CT (yes/no) | 8/3 | 4/1 | 1.000 | Side for Adx (left/right) | 5/6 | 5/0 | 0.058 |
| After Adx | Evaluation time after Adx (month) | | | 0.422 | Histological diagnosis (adenoma/cortical nodule) | 9/2 | 5/0 | 0.458 | Presence of hypokalemia (%) | 0 | 0 | 1.000 | SBP (mmHg) | | | 0.331 | DBP (mmHg) | | | 0.909 | Medication (defined daily dose) | | | 0.950 | eGFR (mL/min/1.73 m2) | | | 0.734 | Basal PRA (ng/mL/h) | | | 0.020 | Basal PAC (ng/dL) | | | 0.047 | Basal ARR | | | 0.002 | U-Aldo (μg/day) | | | 0.428 |
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Adx: unilateral adrenalectomy; SBP: systolic blood pressure; DBP: diastolic blood pressure; Medication: antihypertensive medication; eGFR: estimated glomerular filtration rate; PRA: plasma renin activity; PAC: plasma aldosterone concentration; ARR: aldosterone-renin ratio; U-Aldo: 24 h urine aldosterone; AVS: adrenal venous sampling; LR: lateralized ratio; CR: contralateral ratio; CT: computed tomography. Data are presented as deviation. The Wilcoxon signed-rank test or Fisher’s exact test is performed. value < 0.05. |