Bioinformatics Analysis of the Inflammation-Associated lncRNA-mRNA Coexpression Network in Type 2 Diabetes

Table 2

The top 12 dysregulated lncRNAs in type 2 diabetes mellitus.

lncRNA	Sequence	Regulation		value	Chr	Target mRNA
A1BG-AS1	ATATTGCTGAGCACCTGCTGCATGCTCTCTGTCCTGCTCAGAGCCAGTACCTGGATGGAG	Up	3.87	<0.05	Chr19	CCR10, MGAT1, CIITA, FPR3, MAPK12, LILRB4, GNAI2, AOC3, CCL19, SUFU, DBH, CD72, PLA2G7, MMP14, LILRB1, SLAMF1, CNTNAP1, ITGB2, PTGDS, ALDH1A3
AC084125.4	TTCTCTGTCCAGTTCCGGGAAAGCACTGGCCGTCCTGCCTGCCTGTGGCTGTTCCTGCTA	Up	3.14	<0.05	Chr8	TAF6L, POLR3GL, SCRIB, ABCB8, GPR35, VPS28
RAMP2-AS1	GTAAAAAGTGCTAGGGCCTTCTACACCTTGAAATTATATGTGGAGCATCCTGCAATAAGC	Down	-1.51	<0.05	Chr17	SLC38A3, GAPDH, F7, PRPF6
FTX	AAGGAACAGGTATCTCAGATTCCCAGTTCTCAATCTTCCTTCCTCCTTACAAGATACAAG	Up	2.23	<0.05	chrX	MIF, GAPDH, IDS, HNRNPA1L2
	AGGGTCCTCTCAGTGATTAAGGATTATGAAGTATTAATTCTTCCACTGATATCTCAAAAG	Down	-1.9
DBH-AS1	ATCAGCCACTGCTGTGATATACTGAGCACCTCCTCTAGAGAGAATAAAGGACTGACAAAG	Down	-1.10	<0.05	Chr9	PML, CIITA, MAPK12, LILRB4, CCL19, DBH, CD72, LILRB1, SLAMF1, ANK1, ITGB2
LOXL1-AS1	TTCCAAGGAGAAGCTCTGGAAAGTTCTGCCTGTCTCAGCACCTGGCTGGATCGGAAACGA	UP	2.88	<0.05	Chr15	PIAS2, RPS21, PRPF6
LINC00893	AAGTCAGTATTCACTTAAGCACTCCAAATTACCCAGCACACCCTGCCTGCATGGCGCTGC	Up	1.47	<0.05	chrX	RHOA, ABCC10
	GTGCAAAGTATGTCAGAAAGCAGATGGAAGCCAGGCCCCCTCCTGAAAGAGGCTCCTTGA	Down	-1.22
LINC00894	TGGGTCATCCAGGAAACATACTCACCACTGTCTGTTCTCTGAGTTTTCATTTCCAGGCAT	Up	3.3	<0.05	chrX	ABCC10, KMT2B, IKBKB, TJAP1, LAT
	GCAGCAGGTGAGTTTCCTCACTTGGGTTTCACTGTCAGCATTTTAAAAAGGCAAACTGGT	Down	-1.34
PVT1	AACTATTAAGGGGAAACAAAAGTGTTCTTAGGAGTCCTGCTGTCACTGTGGATTGAGCCG	Up	2.12	<0.05	Chr8	MYC, SCRIB, KMT2B, IKBKB, LAT, TJAP1
	AGGGTTGAGATCTCTGTTTACTTAGATCTCTGCCAACTTCCTTTGGGTCTCCCTATGGAA	Down	-1.75
RUSC1-AS1	ATTTTCAAGTGTCTCTACGTAGCTAAAATCCCAAGCTTCCCTTCCCTATCCCAAATATTG	Down	-1.47	<0.05	Chr1	TJAP1, LAT
HCG25	GGTATAGCCATCCTTATCATCAAACCCTCTTTTCTGGTATTCTCTCAATCCAGTCTTTCA	Up	1.92	<0.05	Chr6	TJAP1
ATP1B3-AS1	AAATGCATTTAAAACCTTAAGGGGACCCAGCACTCCATCCAAGCTTATCTATGCAGCCTG	Up	2.24	<0.05	Chr3	LAT