Fuzzy Data Mining and Bioinformatics Analysis in Methylation Analysis of M6A Gene Promoter Region in Esophageal Cancer

Table 2

Univariate analysis of prognosis in EC patients.

Indicators			Survival rate (%)
			1 year	2 years	3 years
Age (years old)	<65	54	75.9	51.9	38.9	0.213	0.098
	≥65	26	88.5	65.4	46.2
Gender	Male	47	83.0	55.3	38.3	2.358	0.001
	Female	33	84.8	57.6	45.5
Tumor grade	High	59	81.4	55.9	47.5	3.065	0.001
	Middle	16	87.5	56.3	43.8
	Low	5	60.0	20.0	0.0
TNM staging	IIa/IIb	34	82.4	67.6	52.9	2.117	0.001
	III/IV	46	89.1	69.6	45.7
Tumor infiltration	T1/T2	29	86.2	72.4	48.3	2.229	0.001
	T3	51	76.5	45.1	33.3
ALKBH5	Yes	55	69.1	47.3	30.9	3.513	0.001
	No	25	88.0	64.0	40.0
HNRNPC	Yes	46	60.9	37.0	32.6	3.370	0.001
	No	34	79.4	47.1	35.3
METTL3	Yes	58	70.7	48.3	32.8	2.694	0.001
	No	22	86.4	59.1	36.4
METTL14	Yes	16	87.5	68.8	37.5	0.513	0.067
	No	64	89.1	67.2	40.6
WTAP	Yes	55	78.2	49.1	32.7	0.448	0.093
	No	25	80.0	56.0	36.0
RAM15	Yes	51	76.5	47.1	35.3	0.550	0.088
	No	29	82.8	58.6	34.5
YTHDC1	Yes	53	77.4	49.1	37.7	3.357	0.001
	No	27	85.2	66.7	33.3
YTHDF1	Yes	49	83.7	51.0	32.7	0.215	0.102
	No	31	87.1	54.8	35.5
YTHDF2	Yes	29	79.3	51.7	31.0	0.134	0.083
	No	51	76.5	54.9	33.3
FTO	Yes	66	81.8	45.5	31.8	0.209	0.114
	No	24	83.3	54.2	33.3