Design and Development of Biosensors for Progesterone Detection

Figure 4

Schematic illustration of NIR-to-NIR signal-based LRET system for detection of progesterone via competitive immunoassay. Inert-core/active-shell/inert-ultrathin-shell lanthanide-based upconverting nanoparticle donors achieved greatly enhanced LRET efficiencies when combined with a compact progesterone/horseradish peroxidase/IRdyeQC-1 complex acceptor (P-HRP-dye), compared with conventional donors and acceptors [44]. Images reproduced with permission.