Prognostic and Risk Factors in Patients with Locally Advanced Cutaneous Squamous Cell Carcinoma of the Trunk and Extremities

Table 1

Demographic, clinical, therapeutic, and pathological characteristics of patients with locally advanced cutaneous squamous cell carcinoma of trunk and extremities.

Characteristics	n (%)	Characteristics	n (%)
Gender		Lymph node metastasis location
Male	32 (58.2)	Axila	15 (60.0)
Female	23 (41.8)	Groin	10 (40.0)
Race		Lymph node metastasis treatment
Caucasian	49 (89.1)	Linphadenectomy	28 (93.3)
African	6 (10.9)	No treatment	2 (6.7)
Residence		Local or lymph node recurrence after lymphadenectomy
Rural	9 (16.4)	No	13 (46.4)
Urban	46 (83.6)	Local	8 (28.6)
		Lymph node	7 (25.0)
Chronic sun exposure		Distant metastasis
Yes	27 (49.1)	No	58 (92.1)
No	12 (21.8)	Cutaneous	1 (1.6)
n.a.	16 (29.1)	Visceral	4 (6.3)
Anatomical localization		Lymph node metastasis treatment
Lower extremities	22 (40.0)	Linphadenectomy	24 (96.0)
Upper extremities	23 (41.8)	No treatment	1 ( 4.0)
Trunk	10 (18.2)
Non-cancer previous lesion		Tumor grade
Yes	13 (23.6)	I	25 (45.5)
No	42 (76.4)	II	27 (49.0)
		III	3 (5.5)
T classification		Intratumoral lymphocitic infiltrate
T3	33 (60.0)	Negative	12 (21.8)
T4	22 (40.0)	Positive	43 (78.2)
N classification		Peritumoral lymphocitic infiltrate
N0	41 (74.5)	Negative	9 (16.4)
N1	14 (25.5)	Positive	46 (83.6)
Clinical stage		Vascular infiltrate
II	27 (49.1)	Negative	48 (87.3)
III	28 (50.9)	Positive	7 (12.7)
Treatment of primary tumor		Perineural infiltrate
surgery		Negative	54 (98.2)
Local resection with primary closure	1 ( 1.9)	Positive	1 (1.8)
Local resection with reconstruction	18 (32.7)
Amputation/disarticulation	21 (38.2)
Local resection with open wound	5 ( 9.1)
Radiation therapy	8 (14.5)
No treatment	2 (3.6)

n.a.: not available.