Prognostic and Risk Factors in Patients with Locally Advanced Cutaneous Squamous Cell Carcinoma of the Trunk and Extremities

Table 4

Comparative specific cancer survival rates according to immunohistochemical primary tumor expression in patients with locally advanced cutaneous squamous cell carcinoma of trunk and extremities.

Variable	5-year survival (%)	S.E.	p
EGFR
Negative	52.1	10.8	0.592
Positive	34.6	25.3
HER-2
Negative		All cases negative
Positive
HER-3
Negative	0.0	0.0	0.231
Positive	52.5	10.3
HER-4
Negative	49.6	12.4	0.632
Positive	44.0	17.0
Membrane E-cadherin
Negative	38.3	12.7	0.112
Positive	65.5	13.9
Cytoplasm E-cadherin
Negative	35.6	12.5	0.296
Positive	72.5	11.8
Podoplanin
Negative	71.9	10.1	0.018
Positive	23.5	13.2