Ulcerative Granular Cell Tumor: A Clinicopathological and Immunohistochemical Study

Table 1

The clinicopathological and immunohistochemical features of ulcerative GCT.

Clinical data
(i) Age (years)
Range	17–42 y.
Mean ± SD	31.5 ± 7.42
(ii) Sex
Males/females	11/3
Ratio	3.6 : 1
(iii) Duration of the lesion (months)
Range	23–51 m.
Mean ± SD	37.2 ± 8.32
(iv) Time of 2ry ulceration (months)
Range	19–41 m.
Mean ± SD	31.5 ± 6.71
(v) Location
Extremities	12 (5 arm, 2 forearm, 3 foot, 1 leg and 1 thigh)
Anogenital	1 scrotum and 1 perineum
(vi) Size of the base (cm)
Range	3.8 × 3.5–5.2 × 5.1
Average	4.1 × 3.9
Histological features
(I) Epidermal changes	Acanthosis: 11
	Pseudoepitheliomatous hyperplasia: 3
(ii) Cellular infiltrate	Dermal: 12
	Dermal and subcutaneous: 2
(iii) Appendageal infiltrate	Muscle infiltrate: 14
(iv) PAS stain	Strong positive: 10
	Weak positive: 4
Immunohistochemical features
(i) Positive staining	S100 and NSE: 14 (all strong)
	Vimentin: 7 (6 strong–1 weak)
	CD68 : 5 (all weak)
(ii) Negative staining	Desmin, HMB45, EMA and CK