Melanoma-Targeted Chemothermotherapy and In Situ Peptide Immunotherapy through HSP Production by Using Melanogenesis Substrate, NPrCAP, and Magnetite Nanoparticles
Figure 5
Melanoma growth and survival of melanoma-bearing mice by CTI therapy using NPrCAP/M with and without AMF exposure. (a) Experimental protocols. (b) Tumor volumes of rechallenge melanoma transplants on day 13 of after transplantation. (c) Kaplan-Meier survival of melanoma-bearing mice after treatment following experimental protocols of Figure 5(a).
(a) Protocols of Groups I, II, III, and IV of experimental mice
(b) Tumor volumes of rechallenge B16F1 melanoma transplants