Dual S-100-AE1/3 Immunohistochemistry to Detect Perineural Invasion in Nonmelanoma Skin Cancers

<div>Perineural invasion of squamous cell carcinoma (brown) inside the perineurium of the nerve (red). (a) IHC with dual staining for S-100 and AE1/3, original magnification ×200. Squamous cell carcinoma (brown) surrounding nerve, focally penetrating perineurium, and within fascicles. (b) IHC with dual staining for S-100 and AE1/3, original magnification ×200. IHC: immunohistochemistry.</div>

Journal of Skin Cancer

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Figure 1

Figure 1: Dual S-100-AE1/3 Immunohistochemistry to Detect Perineural Invasion in Nonmelanoma Skin Cancers 