Dual S-100-AE1/3 Immunohistochemistry to Detect Perineural Invasion in Nonmelanoma Skin Cancers

Figure 2

Comparative analysis between routine H&E examination and dual IHC using antibodies for S-100 and AE1/3 in the evaluation of PNI in cases of BCC and SCC. PNI: perineural invasion; H&E: hematoxylin and eosin; IHC: immunohistochemistry; BCC: basal cell carcinoma; SCC: squamous cell carcinoma.