MDM4 Isoform Expression in Melanoma Supports an Oncogenic Role for MDM4-A

Figure 2

MDM4 is frequently amplified in melanoma, in contrast with MDM2. Skin cutaneous melanoma data from TCGA with copy number data available for tumor and matched normal tissue (blood) were analyzed for amplification or deletion of the genes MDM2 (a) and MDM4 (b). Copy number is relative to the control blood specimens.

(a)

(b)