MDM4 Isoform Expression in Melanoma Supports an Oncogenic Role for MDM4-A

Figure 4

MDM4 isoform expression in normal skin. Non-sun-exposed (suprapubic) skin specimen data from 604 subjects and sun-exposed (lower leg) skin specimens from 701 subjects were analyzed in the GTEx data portal. Normalized reads × 100 for each indicated isoform of MDM4 are displayed (y-axis). Isoforms are labeled using their common names or Ensembl numbers. Ensembl transcript evidence level 1 (TSL1) transcripts are in bold. This Ensembl transcript (ENST00000470908.5) shares a name with the transcript commonly called MDM4-211 (ENST00000367183.7). Two transcripts encode MDM4-S.