Quantitative Evaluation of Acetaminophen in Oral Solutions by Dispersive Raman Spectroscopy for Quality Control
Table 3
Solutions of different concentrations (160, 200, and 240 mg/mL) used to calculate the precision (RSD) and accuracy (AC).
| | Real concentration (mg/mL) | VO RS/PLS (mg/mL) | DAC (mg/mL) | SD (mg/mL) | RSD (%) | AD (mg/mL) | RD (%) | AC (%) |
| | 160 | 168.5 | 167.7 | 1.0 | 0.6 | −7.7 | −4.6 | 104,8 | | 166.8 | | 168.1 | | 167.1 | | 169.2 | | 166.7 |
| | 200 | 194.9 | 197.8 | 2.9 | 1.5 | −2.2 | −1.1 | 99.0 | | 198.2 | | 198.2 | | 195.6 | | 196.4 | | 203.1 |
| | 240 | 223.6 | 224.8 230.1** | 13.4 4.0** | 6.0 1.7** | −9.9** | −4.3** | 98.5 | | 232.5 | | 233.2 | |
*198.5 | | 228.9 | | 232.3 |
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Outlier, recalculated values after outlier being excluded.
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