Low-Content Quantitation in Entecavir Tablets Using 1064 nm Raman Spectroscopy

Table 4

The actual and predicted API content and the percentage of predicted API in the drug content calculated by the best performance model.

Test set sample	Acceptance API content	Predicted API content (mg)
Baraclude 0.5 mg (90%–105%)	0.45–0.53 mg	0.47
Baraclude 0.5 mg (90%–105%)	0.45–0.53 mg	0.45
Baraclude 1.0 mg (90%–105%)	0.9–1.05 mg	0.93
Baraclude 1.0 mg (90%–105%)	0.9–1.05 mg	0.91
0.5% (w/w%)	0.5%	0.55
0.5% (w/w%)	0.5%	0.50