Considerations in Raman Spectroscopy for Real-Time API Concentration Measurement at Tablet Press Feed Frame

Figure 10

(a) Raman spectra of blends of API (8%, 9%, 10%, 11%, 12%, 13%, 14%, and 15%) in MCC, (b) predicted vs. actual training for APAP in MCC, (c) predicted vs. actual cross validation for APAP in MCC, and (d) predictions from PLS models at varying feeder RPM of feed frame.

(a)

(b)

(c)

(d)