Considerations in Raman Spectroscopy for Real-Time API Concentration Measurement at Tablet Press Feed Frame

Figure 5

(a) Raman spectra of pure MCC (blue) and resultant spectra after fluorescent material spectra subtraction, (b) Raman spectra after baseline correction, (c) Raman spectra after smoothing, and (d) Raman spectra of 10% APAP in MCC after corrections (green), 10% APAP in lactose (yellow), and pure APAP (red).

(a)

(b)

(c)

(d)