Protective Effect of Liposome-Encapsulated Glutathione in a Human Epidermal Model Exposed to a Mustard Gas Analog

Table 1

Liposome composition.

Type of liposomes
	Blank	GSH	NAC	AT	GT	ALA
Lipid components	Concentration (mole fractions)
Phospholipon 90G	0.71	0.71	0.71	0.70	0.70	0.70
cholesterol	0.29	0.29	0.29	0.28	0.28	0.28
α-tocopherol	0	0	0	0.02	0	0
γ-tocopherol	0	0	0	0	0.02	0
α-lipoic acid	0	0	0	0	0	0.02
Aqueous* components	Concentration (mM)
GSH	0	200	0	0	0	0
NAC	0	0	200	0	0	0

*All aqueous components were used as solutions in sterile PBS; liposomes that do not contain aqueous components were prepared with sterile PBS also.
Blank: Blank liposomes (contain no antioxidant); GSH: reduced glutathione; NAC: N-acetyl-L-cysteine; AT: alpha-tocopherol; GT: gamma-tocopherol; ALA: alpha-lipoic acid.