Research Article

Subchronic Hepatotoxicity Evaluation of 2,3,4,6-Tetrachlorophenol in Sprague Dawley Rats

Table 1

Study design showing number of male SD rats assigned per TCP dose group and time point.

Time point (animal necropsy) TCP dose (mg/kg/day)1
02 10 25 50 100 200

5 days111010101010
2 weeks111010101010
4 weeks111010101010
13 weeks121010101010

1TCP doses were prepared in olive oil vehicle and administered daily, 7 days/week.
2Olive oil only.