Tramadol Induced Adrenal Insufficiency: Histological, Immunohistochemical, Ultrastructural, and Biochemical Genetic Experimental Study

Figure 6

Rat adrenal cortex labeled for caspase-3 of the control group (a and b) showing negative expression; Group II (c and d) showing high expression along the adrenal cortex; Group III showing high expression in ZG and ZR (e) and moderate expression in ZR (f); Group IV (g and h) showing few scattered immunopositive cells among ZF (arrow), ×400. Zona glomerulosa (ZG), zona fasciculata (ZF), and zona reticularis (ZR).

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