Evaluation of the Acute Hepatoprotective Potential of Hydroethanolic Extract of Duranta erecta L. Parts

Table 2

Effect of treatment on biochemical markers of animals in CCl4 and Para treatments.

	Normal	CCl4 only	Sily + CCl4	DRL + CCl4	DRR + CCl4	DRU + CCl4	Para only	Sily + Para	DRL + para	DRR + Para	DRU + Para
Total protein (g/L)	64.35 ± 1.63	76.47 ± 1.79	72.73 ± 3.91	65.00 ± 4.89	64.90 ± 1.75	65.35 ± 3.16	76.77 ± 2.97	72.48 ± 1.62	63.30 ± 5.89	62.15 ± 2.21	59.68 ± 2.76
ALB (g/L)	38.05 ± 1.41	38.80 ± 0.72	35.75 ± 1.24	32.00 ± 3.29	35.30 ± 1.12	35.40 ± 0.60	38.60 ± 2.46	38.88 ± 1.78	31.63 ± 2.43	36.85 ± 1.76	33.30 ± 1.26
GLO (g/L)	26.30 ± 1.97	37.67 ± 1.11	36.98 ± 5.05	33.00 ± 2.67	29.60 ± 1.75	29.95 ± 2.73	38.17 ± 5.40	33.60 ± 1.33	31.68 ± 4.48	25.30 ± 2.97	26.38 ± 2.08
ALT (U/L)	50.00 ± 2.31	178.60 ± 6.67^a	39.95 ± 2.10^b	57.55 ± 2.21^b	66.50 ± 4.17^b	69.20 ± 0.83^b	151.33 ± 6.11^a	42.13 ± 3.16^c	74.78 ± 3.94^c	82.78 ± 4.04^c	80.80 ± 3.11^c
AST (U/L)	127.13 ± 6.47	280.85 ± 25.96^a	141.58 ± 8.08^b	229.93 ± 4.77^ab	182.28 ± 4.86^ab	203.58 ± 15.36^ab	348.90 ± 14.32^a	194.18 ± 5.86^ac	251.85 ± 13.11^ab	157.80 ± 15.70^c	256.35 ± 4.65^ab
ALP (U/L)	459.85 ± 15.73	660.00 ± 25.64^a	395.10 ± 16.85^ab	552.48 ± 13.32^ab	349.98 ± 30.79^ab	444.23 ± 43.98^ab	540.67 ± 18.26^a	339.05 ± 26.17^ac	284.70 ± 30.98^ac	227.65 ± 24.00^ac	402.8 8 ± 9.79^ac
GGT (U/L)	10.90 ± 1.05	19.53 ± 0.41^a	9.80 ± 0.38^b	11.23 ± 1.53^b	9.90 ± 1.15^b	9.53 ± 2.14^b	18.30 ± 0.69^a	13.33 ± 0.85	8.03 ± 0.90^c	7.33 ± 0.40^c	13.15 ± 1.67
TBil (mmol/L)	1.67 ± 0.19	5.35 ± 0.20^a	1.64 ± 0.12^b	2.22 ± 0.15^b	2.35 ± 0.36^b	2.29 ± 0.13^b	2.23 ± 0.11	1.54 ± 0.12	2.54 ± 0.18	2.38 ± 0.05	2.58 ± 0.25
DBil (mmol/L)	0.80 ± 0.13	1.04 ± 0.21	0.92 ± 0.09	1.19 ± 0.15	1.21 ± 0.18	0.98 ± 0.04	1.04 ± 0.25	0.73 ± 0.10	1.37 ± 0.14	1.25 ± 0.07	1.02 ± 0.33
IBil (mmol/L)	0.88 ± 0.16	4.31 ± 0.03^a	0.73 ± 0.03	1.03 ± 0.17	1.13 ± 0.36	1.31 ± 0.09	1.20 ± 0.21	0.81 ± 0.10	1.17 ± 0.07	1.14 ± 0.11	2.16 ± 0.10^c
Creat (μmol/L)	27.68 ± 4.09	28.57 ± 4.06	35.95 ± 8.03	11.20 ± 3.83^ab	20.90 ± 2.70	18.96 ± 2.41	27.10 ± 2.78	26.53 ± 2.45	19.38 ± 3.95	11.75 ± 1.67^ac	19.73 ± 1.94
Urea	3.58 ± 0.22	9.89 ± 1.16^a	8.30 ± 1.00	4.99 ± 0.52	6.86 ± 0.41	5.18 ± 0.53	6.60 ± 1.48	5.53 ± 0.87	3.74 ± 0.37	5.42 ± 0.70	5.15 ± 0.29
TChol (mmol/L)	2.53 ± 0.19	3.03 ± 0.43	3.29 ± 0.09	2.04 ± 0.17	2.44 ± 0.22	2.37 ± 0.20	3.24 ± 0.30	3.12 ± 0.13	2.01 ± 0.14	2.07 ± 0.14	1.49 ± 0.19
Trig (mmol/L)	1.67 ± 0.22	0.90 ± 0.09	0.90 ± 0.09	1.27 ± 0.30	0.62 ± 0.15	0.87 ± 0.13	1.62 ± 0.19	1.07 ± 0.13	1.48 ± 0.59	0.98 ± 0.26	0.87 ± 0.25
VLDL (mmol/L)	0.75 ± 0.09	0.40 ± 0.06	0.40 ± 0.04	0.58 ± 0.13	0.30 ± 0.07	0.40 ± 0.07	0.73 ± 0.09	0.50 ± 0.04	0.40 ± 0.12	0.68 ± 0.26	0.71 ± 0.20

Statistical significance: ^a–0.001 from normal; ^b–0.001 from CCl₄ only; ^c–0.001 from Para only.