Hepatoprotective Effect of Corm of Ensete ventricosum (Welw.) Cheesman Extract against Isoniazid and Rifampicin Induced Hepatotoxicity in Swiss Albino Mice

Table 2

Effect of corm of Ensete ventricosum (Welw.) Cheesman extract on liver enzyme parameters and serum total bilirubin (TBIL) in isoniazid and rifampicin challenged mice.

Groups	ALT (IU/L)	AST (IU/L)	ALP (IU/L)	TBIL
Group I (normal control)	34.66 ± 3.42^a	53.67 ± 4.40^a	98.33 ± 2.49^a	0.12 ± 0.01^a
Group II (INH and RIF)	123.67 ± 3.25^d	152.83 ± 3.84^d	171.00 ± 4.69^c	0.28 ± 0.02^b
Group III (extract 200 mg/kg)	90.00 ± 4.89^c	87.50 ± 4.96^c	120.83 ± 3.75^b	0.21 ± 0.03^ab
Group IV (extract 400 mg/kg)	53.17 ± 4.95^b	75.33 ± 3.21^bc	108.00 ± 4.09^ab	0.19 ± 0.03^a
Group V (silymarin control)	40.16 ± 3.09^ab	62.17 ± 1.62^ab	106.33 ± 2.40^ab	0.13 ± 0.01^a

The results are expressed as mean ± SE. Values with different superscripts within the same column are statistically significant ().