Toxicological Profile of the Aqueous Extract of Tectona grandis L.F. (Verbenaceae) Leaves: A Medicinal Plant Used in the Treatment of Typhoid Fever in Traditional Cameroonian Medicine

Table 3

Effect of aqueous extract of T. grandis leaves on relative organ weights of animals.

Groups	Liver (g)	Kidneys (g)	Spleen (g)	Lungs (g)	Heart (g)	Gonads (g)
Males
Control	3.20 ± 0.18^a	0.64 ± 0.04^a	0.27 ± 0.10^a	0.51 ± 0.08^a	0.27 ± 0.01^a	0.92 ± 0.04^a
30 mg/kg	3.10 ± 0.11^a	0.63 ± 0.02^a	0.30 ± 0.10^a	0.50 ± 0.06^a	0.29 ± 0.02^a	0.97 ± 0.12^a
90 mg/kg	3.09 ± 0.29^a	0.62 ± 0.02^a	0.29 ± 0.05^a	0.51 ± 0.03^a	0.28 ± 0.01^a	0.96 ± 0.09^a
270 mg/kg	3.45 ± 0.58^a	0.68 ± 0.11^a	0.37 ± 0.19^a	0.57 ± 0.18^a	0.31 ± 0.03^a	0.96 ± 0.04^a
810 mg/kg	3.08 ± 0.29^a	0.65 ± 0.05^a	0.20 ± 0.03^a	0.43 ± 0.04^a	0.28 ± 0.04^a	0.92 ± 0.10^a
Females
Control	3.20 ± 0.41^a	0.63 ± 0.07^a	0.27 ± 0.09^a	0.60 ± 0.09^a	0.31 ± 0.03^a	0.05 ± 0.01^a
30 mg/kg	3.33 ± 0.25^a	0.64 ± 0.05^a	0.33 ± 0.07^a	0.49 ± 0.04^a	0.28 ± 0.03^a	0.04 ± 0.01^a
90 mg/kg	3.16 ± 0.24^a	0.63 ± 0.04^a	0.32 ± 0.08^a	0.48 ± 0.09^a	0.30 ± 0.02^a	0.05 ± 0.01^a
270 mg/kg	3.17 ± 0.10^a	0.65 ± 0.04^a	0.26 ± 0.06^a	0.53 ± 0.05^a	0.33 ± 0.05^a	0.05 ± 0.01^a
810 mg/kg	2.96 ± 0.10^a	0.63 ± 0.04^a	0.25 ± 0.10^a	0.52 ± 0.08^a	0.29 ± 0.02^a	0.05 ± 0.01^a

Data are expressed as mean ± SD, n = 4. Values for a given group in a column followed by a different letter as superscript are significantly different according to Waller–Duncan’s multiple comparison test ( < 0.05).