Effect of Coated Silver Nanoparticles on Cancerous vs. Healthy Cells

Figure 4

Morphological changes of Hep-2 cells exposure Ag NPs. The cells morphology after Ag NPs treatment were analyzed by fluorescent microscopy after staining with acridine orange. NPs at concentrations 10 and 2 μg/mL lead to significant morphological changes in cancer Hep-2 cells such as pyknosis of nuclear chromatin and loses of the cytoplasm contents. Red arrows show necrotic cells and blue arrows − mitotic cells (280× magnification).