Research Article

Acute and Subchronic Toxicity Studies on the Aqueous Extract of the Plant Mixture (Bidens pilosa and Cymbopogon citratus Aerial Parts) in Rat Model

Table 3

Effects of the plant mixture aqueous extract on the relative weight of the organs of males.

OrgansTNTSATBC 200BC 400BC 800SAT

Relative weight (%)Liver3.01 ± 0.112.87 ± 0.082.70 ± 0.162.83 ± 0.122.69 ± 0.062.64 ± 0.08
Kidneys0.53 ± 0.030.50 ± 0.010.57 ± 0.030.55 ± 0.010.54 ± 0.030.51 ± 0.02
Heart0.29 ± 0.010.29 ± 0.020.30 ± 0.010.31 ± 0.010.30 ± 0.020.28 ± 0.02
Lungs0.63 ± 0.090.54 ± 0.040.63 ± 0.050.60 ± 0.060.59 ± 0.050.58 ± 0.05
Brain0.66 ± 0.040.65 ± 0.010.71 ± 0.020.71 ± 0.020.72 ± 0.010.68 ± 0.03
Spleen0.42 ± 0.020.32 ± 0.010.35 ± 0.020.37 ± 0.010.38 ± 0.050.36 ± 0.02

Each value represents the mean ± SEM. n = 5. TN: normal rats receiving distilled water (10 mL/kg); TSAT: normal satellite observed 14 more days after stopping every treatment; BC 200, BC 400, and BC 800: animals receiving the aqueous extract of the mixture of B. pilosa and C. citratus at the respective doses of 200, 400, and 800 mg/kg; SAT: satellite extract at the dose of 800 mg/kg observed 14 days after stopping every treatment.