In Vitro and In Vivo Toxicological Evaluation of Avicennia africana P: Beauv. (Avicenniaceae) Leaf Extract in a Rat Model

Table 4

Relative organ weights (ROWs) of animals treated with the AAE in subacute toxicity tests.

Relative organ weight (mgkg^−1)
Organ	Control	100	300	1000	value
Liver	2.84 ± 0.30	3.40 ± 0.04	2.98 ± 0.22	3.51 ± 0.08	0.100
Kidney	0.65 ± 0.06	0.66 ± 0.03	0.61 ± 0.03	0.65 ± 0.05	0.526
Heart	0.42 ± 0.05	0.39 ± 0.01	0.43 ± 0.02	0.43 ± 0.01	0.372
Spleen	0.27 ± 0.04	0.35 ± 0.07	0.26 ± 0.02	0.27 ± 0.04	0.150

Organ body indices of AAE-treated rats with the negative control group. The values are given as mean ± S.E.M. (n = 5). The data were analysed using one-way ANOVA with ().