Research Article

Evidence on the Heroin-Mediated Impairment of the Oxidative Status of Erythrocytes

Table 2

Correlation analysis of studied serum redox markers and addiction profile data of chronic heroin addiction subjects. A significant correlation was evident for [GPX-1] and carbonyl contents with the duration of addiction ().

ParametersCorrelationDATLADAD

[Met-Hb]Coefficient (r)−0.2600.315-0.206
value0.270.140.38

[GPX-1]Coefficient (r)−0.5090.1470.029
value0.020.540.90

GPX activityCoefficient (r)−0.2900.282−0.033
value0.220.230.90

CarbonylcontentsCoefficient (r)−0.612−0.075−0.040
value0.010.800.90

GSSG/GSHCoefficient (r)0.431−0.1350.131
value0.110.630.65

DA: duration of addiction in years; TLAD: timing of the lad administrated dose (days); AD: administrated dose. It is statistically significant with