Teratogenic Evaluation of 80% Ethanol Extract of Embelia schimperi Vatke Fruits on Rat Embryo and Fetuses
Table 11
Number of ossification centers in the appendicular skeleton of rat fetuses from experimental groups treated with the 80% ethanol fruit extract of Embelia schimperi.
Group
Forelimb phalanges
Hindlimb phalanges
Metacarpus
Metatarsus
Group I (250 mg/kg)
3.77 ± 0.32
3.51 ± 0.42
3.9 ± 0.31
4.09 ± 0.31
Group II (500 mg/kg)
3.83 ± 0.26
3.47 ± 0.37
3.8 ± 0.41
4.02 ± 0.22
Group III (1000 mg/kg)
3.67 ± 0.43
3.43 ± 0.51
3.9 ± 0.26
3.99 ± 0.33
Group IV (pair-fed)
3.91 ± 0.28
3.61 ± 0.33
3.93 ± 0.24
4.13 ± 0.18
Group V (ad libitum)
3.88 ± 0.41
3.73 ± 0.29
3.87 ± 0.35
4.17 ± 0.02
Results are presented as the mean ± standard deviation from the mean of ossification centers count, one-way ANOVA.