Teratogenic Evaluation of 80% Ethanol Extract of Embelia schimperi Vatke Fruits on Rat Embryo and Fetuses

Table 9

External gross malformations after treatment with the 80% ethanol fruit extract of Embelia schimperi.

Group	Proportion of external malformations (%)
	Nervous system defects			Musculoskeletal defects			Others
	ExE	AnE	SB	KY	SC	LD	MT	EGA
Group I (250 mg/kg)	0	0	0	0	0	0	0	0
Group II (500 mg/kg)	0	0	0	0	0	0	0	0
Group III (1000 mg/kg)	0	0	0	0	0	0	0	0
Group IV (pair-fed)	0	0	0	0	0	0	0	0
Group V (ad libitum)	0	0	0	0	0	0	0	0

Results are expressed in terms of proportions of malformations, chi-square test; ExE: exencephaly, AnE: anencephaly, SB: spina bifida, KY: kyphosis, SC: scoliosis, LD: limb defect, MT: missed tail, and EGA: external genitalia agenesis.