Quercetin Zinc and Iron Metal Complexes Protect against Sodium Arsenite Intoxication in the Hepato-Renal System of Wistar Rats via the Oxidative Stress Pathway

Figure 7

Magnified views of a liver micromorphological section demonstrated by hematoxylin and eosin staining at high magnification (×400). The hepatocytes, sinusoids, and portal triad (hepatic vein, hepatic artery and bile duct) are all visible across the various groups. (a) Normal control (normal rats); (b) NaAr-induced toxicity (sodium arsenate-intoxicated rat); (c) NaAr-Quer (sodium arsenate-intoxicated rat + 30 mg/kg quercetin treatment); (d) NaAr-Quer + Zn (sodium arsenate-intoxicatedrat + quercetin-Zn complex treatment); (e) NaAr-Quer + Fe (sodium arsenate-intoxicatedrat + quercetin-Fe complex treatment). Red arrow = the sinusoids appeared mildly infiltrated and some hemorrhage was observed across the profiles. Black arrow = the sinusoids appearing normal. B = bileduct; HA = hepatic artery; HV = hepatic vein; H = hepatocytes; P = parenchyma; and S = sinusoid.