Acute and Repeated Dose 28-Day Oral Toxicity Study of the Aqueous Extracts from the Leafy Stem and Fruit of Pedalium murex D.Royen EX.L in Wistar Rats

Figure 3

Photomicrographs of hematoxylin and eosin (H & E, under ×20 magnification power) stained sections of the liver (M–O), kidney (P–R), and testis (S–U) from rats treated with 200 mg/kg, 400 mg/kg, and 800 mg/kg of P. murex fruit aqueous extract for 28 days consecutively. Indicators: centrilobular vein (V), hepatic cord (H), sinusoids (S), glomerular (G), Bowman’s space (BS), convoluted tubules (CT), seminiferous tubules (ST), interstitial tissue (IT), dilated Bowman’s space (DB), pyknotic nucleus cells (PN), and empty renal corpuscle (ER).