Research Article

Acute and Repeated Dose 28-Day Oral Toxicity Study of the Aqueous Extracts from the Leafy Stem and Fruit of Pedalium murex D.Royen EX.L in Wistar Rats

Table 1

Body weight gain and food intake of rats treated with the aqueous extracts of P. murex leafy stem (LS) and fruit (FR).

ControlLS5000FR5000

Initial body weight (g)192.83 ± 7.97201.17 ± 7.15206.67 ± 6.85
Week 1 (g)212.33 ± 4.33220 ± 4.80227 ± 4.27
Week 2 (g)217 ± 3.46223.5 ± 4.19233.33±2.32
Body weight gain (%)11.20 ± 2.2810.04 ± 1.7211.47 ± 2.09
Food intake (g/day)54.18 ± 1.4366.82±1.5564.86±1.58

Values are expressed as the mean ± SEM. value was considered significant using Kruskal–Wallis test followed by Dunn’s multiple comparison test. Asterisk denotes difference compared with the control group.