Acute and Repeated Dose 28-Day Oral Toxicity Study of the Aqueous Extracts from the Leafy Stem and Fruit of Pedalium murex D.Royen EX.L in Wistar Rats

Table 2

Mean relative organ weight (%) of rats 14 days after single oral administration of the aqueous extracts of P. murex leafy stem (LS) and fruit (FR).

Organs	Control	LS5000	FR5000
Liver	4.21 ± 0.07	4.33 ± 0.06	4.23 ± 0.18
Kidneys	0.35 ± 0.02	0.37 ± 0.01	0.35 ± 0.01
Spleen	0.46 ± 0.03	0.38 ± 0.04	0.38 ± 0.04
Stomach	1.02 ± 0.08	1.06 ± 0.08	1.11 ± 0.06
Heart	0.36 ± 0.01	0.40 ± 0.04	0.34 ± 0.01
Lungs	0.89 ± 0.06	0.81 ± 0.03	0.75 ± 0.01

Values are expressed as the mean ± SEM (n = 3). value was considered significant using the Kruskal-Wallis test followed by Dunn’s multiple comparison test.