Acute and Subacute Toxicity of Rhamnus prinoides Leaves on Histopathology of Liver, Kidney, and Brain Tissues, and Biochemical Profile of Rats

Table 3

Organ weight of rats treated with leaf extract of R. prinoides.

Absolute organ weight (g)		Group
		Group I	Group II	Group III	Group IV
Male	Liver	8.92 ± 0.3	8.66 ± 0.2	9.01 ± 0.3	8.72 ± 0.2
	Kidney	0.92 ± 0.05	0.91 ± 0.03	1.10 ± 0.08	0.96 ± 0.06
	Brain	1.92 ± 0.03	1.89 ± 0.02	1.92 ± 0.04	1.98 ± 0.04
Female	Liver	6.62 ± 0.2	6.51 ± 0.2	6.93 ± 0.3	7.11 ± 0.4
	Kidney	0.67 ± 0.02	0.71 ± 0.01	0.76 ± 0.04	0.69 ± 0.01
	Brain	1.85 ± 0.01	1.88 ± 0.08	1.77 ± 0.04	1.83 ± 0.02

Results are expressed as mean ± SE; one-way ANOVA. Group I–III, respectively, received 250, 500, and 1000 mg/kg of R. prinoides extract and group IV: control.