Research Article

Phytochemical Screening, Antioxidant Activity, and Acute Toxicity Evaluation of Senna italica Extract Used in Traditional Medicine

Table 5

Biochemical parameters of rats.

IndexesControlAEEE

Glucose (g/L)D00.64 ± 0.020.55 ± 0.030.60 ± 0.01
D140.79 ± 0.06/a0.66 ± 0.02b0.69 ± 0.01/b

Urea (g/L)D00.21 ± 0.020.24 ± 0.030.25 ± 0.02
D140.20 ± 0.00/a0.44 ± 0.02/b0.22 ± 0.02/a

Creatinine (mg/L)D010.33 ± 0.8410.07 ± 0.269.78 ± 8.86
D1411.67 ± 0.339.05 ± 0.548.78 ± 0.69

ALT (UI/L)D056.96 ± 5.05/a60.06 ± 4.16/b36.68 ± 1.92/c
D1414.66 ± 0.23/a15.49 ± 1.74/a24.73 ± 3.04/b

AST (UI/L)D021.56 ± 0.55/a25.66 ± 1.18/b31.01 ± 3.45/c
D1418.43 ± 0.06/a24.32 ± 2.15/b27.40 ± 1.11/c

ALP (UI/L)D0460.12 ± 21.18/a495.69 ± 60.21/b503.37 ± 28.80/c
D14438.65 ± 3.43/a895.68 ± 6.21/b577.46 ± 107.29/c

ƴGT(UI/L)D03.61 ± 0.25/a4.66 ± 0.39/b4.82 ± 0.47/b
D143.93 ± 0.05/a3.30 ± 0.04/a4.50 ± 0.39/b

AE: aqueous extract group; EE: ethanolic extract group; AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALP: alkaline phosphatase; ƴGT: gamma glutamyl transferase. Means with letters a; b; c are different (); means with ; ; are different for D0 and D14 of the same parameter. ; ; .