Research Article

Acute and Subchronic Oral Toxicity Evaluation of Herbal Formulation: Piper crocatum Ruiz and Pav., Typhonium flagelliforme (Lodd.) Blume, and Phyllanthus niruri L. in Sprague–Dawley Rats

Table 1

Average relative organ weight of male animals exposed to SKM product acutely.

GroupsNumber (n)Average of relative organ weight (g)
HeartLungStomachLiverKidneyLymph

Control60.38 ± 0.030.76 ± 0.060.77 ± 0.093.22 ± 0.340.64 ± 0.040.28 ± 0.05
SKM 2000 mg/kg b.w.60.32 ± 0.020.85 ± 0.130.86 ± 0.043.72 ± 0.150.73 ± 0.060.31 ± 0.03
SKM 5000 mg/kg b.w.60.32 ± 0.020.71 ± 0.070.87 ± 0.103.30 ± 0.240.62 ± 0.020.27 ± 0.02