Retinal Progenitor Cells Exhibit Cadherin-Dependent Chemotaxis across Transplantable Extracellular Matrix of In Vitro Developmental and Adult Models

Figure 2

Stem-like cells exhibit patterns of adhesion upon different extracellular matrices. Drosophila progenitor cells (DPs) observed upon (A) uncoated Petri dishes (N/A; n = 4), (B) laminin (LM4; n = 10), (C) poly-L-lysine (PLL; n = 6), and (D) concanavalin (Con-A; n = 12) coated Petri dishes at time points t0 (2 hours after seeding to allow for adhesion), t24 (24 hours), t48 (48 hours), and t72 (72 hours) (scale bars: 50 μm). (E) Mouse progenitor cells (MPs) adhered upon uncoated Petri dishes (N/A; n = 8), laminin (LM; n = 8), poly-L-lysine (PLL; n = 8), and matrigel (MG; n = 8) coated Petri dishes at time point t48 (scale bars: 100 μm).