Research Article

Retinal Progenitor Cells Exhibit Cadherin-Dependent Chemotaxis across Transplantable Extracellular Matrix of In Vitro Developmental and Adult Models

Table 1

Summary of growth factors and extracellular matrix (ECM) used to examine the migratory behaviors of retinal progenitors cultured from Drosophila melanogaster (DPs) and from rodent (MPs).

Growth factor examined (Catalog no., manufacturer)ConcentrationSpecies reactivity

Stromal-derived growth factor 1-alpha (SDF1-α; ThermoFisher Catalog #RP-8658)100 ng/mLMPs
Epidermal growth factor (EGF; ThermoFisher Catalog #PHG0311)20 ng/mLMPs
Insulin-like growth factor 1 (IGF1; ThermoFisher Catalog #PHG0071)50 ng/mLMPs
Fibroblast growth factor-8 (FGF-8; ThermoFisher Catalog #RP-87808)10 ng/mLMPs
Pyramus (Pyr; ThermoFisher Catalog #PHG0184)10 ng/mLDPs
Brain-derived neurotrophic factor (BDNF; ThermoFisher Catalog #10908-010)10 ng/mLDPs
Insulin (IN; ThermoFisher Catalog #RP-10908)10 ng/mLDPs
Concanavalin A (ConA; eBioscience, #00-4978-93)15 μg/mLDPs
Laminin (LM; ThermoFisher Catalog #23017015)15 μg/mLDPs and MPs
Matrigel (MAT; Fisher scientific Catalog #CB-40234A)10 μg/mLDPs and MPs
Poly-L-lysine (PLL; Fisher scientific Catalog #A005C)20 μg/mLDPs and MPs