Human Bone Marrow versus Adipose-Derived Stem Cells: Influence of Donor Characteristics on Expandability and Implications for Osteogenic Ex Vivo BMP-2 Regional Gene Therapy

Figure 2

Comparisons of cell counts at each passage between groups. Mann–Whitney U test was used to determine statistical significance between BMSCs and ASCs at each passage. (a) Comparison between bone marrow-derived stem cells and adipose-derived stem cells. Samples per group: P1: 62 BMSCs, 101 ASCs; P2: 58 BMSCs, 95 ASCs; P3: 51 BMSCs, 76 ASCs; P4: 45 BMSCs, 49 ASCs; P5: 38 BMSCs, 46 ASCs. (b) Comparison of adipose-derived stem cells harvested during total knee arthroplasty (TKA) versus arthroscopic knee surgery (AKS). Samples per group: P1: 90 TKA, 11 AKS; P2: 84 TKA, 10 AKS; P3: 66 TKA, 10 AKS; P4: 39 TKA, 10 AKS; P5: 36 TKA, 10 AKS. (c) Comparison of adipose-derived stem cells harvested during TKA/AKS versus liposuction. Samples per group: P1: 101 TKA/AKS, 15 lipo; P2: 95 TKA/AKS, 13 lipo; P3: 76 TKA/AKS, 10 lipo.

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