Research Article

Human Bone Marrow versus Adipose-Derived Stem Cells: Influence of Donor Characteristics on Expandability and Implications for Osteogenic Ex Vivo BMP-2 Regional Gene Therapy

Table 5

Comparison of adipose harvest site and technique.

TKA versus AKSTKA (n = 93)AKS (n = 13) value
MeanSDMeanSD

Age64.678.2737.6214.17<0.001
Sex47 F, 46 M7 F, 6 M0.823
Tissue volume (mL)11.355.355.353.21<0.001
SVF (×106 cells)6.76.781.260.95<0.001
Cell yield/mL (×106 cells/mL)0.570.550.310.330.012

TKA/AKS versus liposuctionTKA/AKS (n = 106)Liposuction (n = 18) value
MeanSDMeanSD

Age61.3512.7239.568.51<0.001
Sex54 F, 52 M18 F, 0 M<0.001
Tissue volume (mL)10.475.13378.61269.53<0.001
SVF (×106 cells)6.036.6151.3936.95<0.001
Cell yield/mL (×106 cells/mL)0.580.550.130.04<0.001

TKA = total knee arthroplasty, AKS = arthroscopic knee surgery, F = female, M = male, SVF = stromal vascular fraction, and SD = standard deviation. Bold p values indicate significance.