Human Bone Marrow versus Adipose-Derived Stem Cells: Influence of Donor Characteristics on Expandability and Implications for Osteogenic Ex Vivo BMP-2 Regional Gene Therapy
Table 5
Comparison of adipose harvest site and technique.
TKA versus AKS
TKA (n = 93)
AKS (n = 13)
value
Mean
SD
Mean
SD
Age
64.67
8.27
37.62
14.17
<0.001
Sex
47 F, 46 M
7 F, 6 M
0.823
Tissue volume (mL)
11.35
5.35
5.35
3.21
<0.001
SVF (×106 cells)
6.7
6.78
1.26
0.95
<0.001
Cell yield/mL (×106 cells/mL)
0.57
0.55
0.31
0.33
0.012
TKA/AKS versus liposuction
TKA/AKS (n = 106)
Liposuction (n = 18)
value
Mean
SD
Mean
SD
Age
61.35
12.72
39.56
8.51
<0.001
Sex
54 F, 52 M
18 F, 0 M
<0.001
Tissue volume (mL)
10.47
5.13
378.61
269.53
<0.001
SVF (×106 cells)
6.03
6.61
51.39
36.95
<0.001
Cell yield/mL (×106 cells/mL)
0.58
0.55
0.13
0.04
<0.001
TKA = total knee arthroplasty, AKS = arthroscopic knee surgery, F = female, M = male, SVF = stromal vascular fraction, and SD = standard deviation. Bold p values indicate significance.