MiR-34a-Functionalized Hydroxyapatite by Lyophilization Promoted Bone Regeneration in Irradiated Bone Defects

<div>Osteogenic differentiation of 2 Gy-irradiated BMSCs in vitro. (a) Intracellular ALP activity after 7 days of osteogenic induction. (b) Gene expression of <i>Runx2</i>, <i>Alp</i>, <i>Bmp2</i>, and <i>Ocn</i> after 14 days of osteogenic induction. (c) Western blot of ALP, RUNX2, BMP2, OCN, and GAPDH after 14 days of osteogenic induction. Quantitative analysis of the Western blot results relative to GAPDH. 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Journal of Tissue Engineering and Regenerative Medicine

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Figure 4

Figure 4: MiR-34a-Functionalized Hydroxyapatite by Lyophilization Promoted Bone Regeneration in Irradiated Bone Defects 