Endothelial Cell-Derived Exosomes Inhibit Osteoblast Apoptosis and Steroid-Induced Necrosis of Femoral Head Progression by Activating the PI3K/Akt/Bcl-2 Pathway

<div>EC-exos characterization and the uptake by osteoblasts. (a) Representative image of exosomes secreted by endothelial cells by transmission electron microscopy. (b) Nanoparticle analysis of EC-exos. (c) Western blotting of exosomal markers CD9, CD63, CD31, and TSG101. (d) The uptake of exosomes in osteoblasts by PKH26 staining. Scale bar = 50 <i>μ</i>m.</div>

Journal of Tissue Engineering and Regenerative Medicine

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Figure 1: Endothelial Cell-Derived Exosomes Inhibit Osteoblast Apoptosis and Steroid-Induced Necrosis of Femoral Head Progression by Activating the PI3K/Akt/Bcl-2 Pathway 

Figure 1 | Endothelial Cell-Derived Exosomes Inhibit Osteoblast Apoptosis and Steroid-Induced Necrosis of Femoral Head Progression by Activating the PI3K/Akt/Bcl-2 Pathway 