Endothelial Cell-Derived Exosomes Inhibit Osteoblast Apoptosis and Steroid-Induced Necrosis of Femoral Head Progression by Activating the PI3K/Akt/Bcl-2 Pathway

<div>H&amp;E staining and IHC staining of femoral heads in rat model with different treatments. (a) H&amp;E staining of the femoral heads in rats receiving different treatments. Scale bar: 200 <i>μ</i>m. (b) IHC staining of p-Akt, Bcl-2, and Bax in samples from the different treatment groups. Scale bar: 50 <i>μ</i>m.</div>

Journal of Tissue Engineering and Regenerative Medicine

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Figure 5

Figure 5: Endothelial Cell-Derived Exosomes Inhibit Osteoblast Apoptosis and Steroid-Induced Necrosis of Femoral Head Progression by Activating the PI3K/Akt/Bcl-2 Pathway 

Figure 5 | Endothelial Cell-Derived Exosomes Inhibit Osteoblast Apoptosis and Steroid-Induced Necrosis of Femoral Head Progression by Activating the PI3K/Akt/Bcl-2 Pathway 