A Novel Epidermis Model Using Primary Hidradenitis Suppurativa Keratinocytes

Figure 2

Staining of the epidermis models of foreskin (f) and hidradenitis suppurativa (HS) keratinocytes. Epidermis models were cultivated for 14 or 21 days at the air-liquid interface. The epidermis equivalents were stained with (a) hematoxylin-eosin as well as (b) anti-filaggrin, (c) anti-involucrin, (d) anti-cytokeratin-10, and (e) anti-Ki-67 antibodies. Representative sections are shown and the values were mean ± SD (n = 3; scale bar = 100 µM; black squares = foreskin; black dots = HS; and black arrows = Ki-67(+) cells). values were calculated using Wilcoxon Mann–Whitney U Test, which showed no statistically significant differences between both groups.

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