Lack of Restoration in Vivo by K+-Channel Modulators of Jejunal Fluid Absorption after Heat Stable Escherichia coli Enterotoxin (STa) Challenge
Figure 1
The effect on control jejunal fluid uptake () in vivo of luminal perfusion with 80 ng/mL E. coli STa alone () and also STa in the presence of 300 uM () luminal glibenclamide, 30 uM luminal clotrimazole (), and 1 uM luminal cromakalim (). Results are presented as the mean and standard error of the mean. Perfusion with STa caused a significant () reduction in fluid uptake that was unaffected by the luminal addition of the potassium channel active agents.
