Hematological and Biochemical Profile of Patients Infected with Schistosoma mansoni in Comparison with Apparently Healthy Individuals at Sanja Town, Northwest Ethiopia: A Cross-Sectional Study

Table 3

Association of S. mansoni parasitic intensity with host hematological and biochemical profiles in Sanja town, northwest Ethiopia, 2019.

Parameter	Control group (0 epg)	Light (1–99 epg)	Moderate (100–399 epg)	Heavy (≥400)	value
	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD
WBC (×10^3/μL)	7.81 ± 3.44	4.93 ± 1.48	4.04 ± 1.69	2.47 ± 1.15	<0.001
L (×10^3/μL)	2.48 ± 1.32	1.61 ± 0.61	1.28 ± .4971	0.93 ± 0.92	<0.001
Mixed (×10^3/μL)	1.55 ± 1.29	0.58 ± 0.50	0.51 ± 0.60	0.43 ± 0.40	<0.001
Granulocyte (×10^3/μL)	4.03 ± 2.07	2.85 ± 1.17	2.22 ± 1.39	1.10 ± 0.17	<0.001
RBC (×10^6/μL)	4.04 ± 0.65	4.21 ± 1.16	3.53 ± 0.39	2.52 ± 0.13	<0.001
Hgb (g/dl)	12.58 ± 1.67	12.04 ± 1.73	10.01 ± 1.19	8.30 ± 1.04	<0.001
PCV (%)	37.51 ± 5.11	35.94 ± 5.02	30.62 ± 3.46	24.87 ± 2.84	<0.001
MCV (μm^3)	86.45 ± 6.94	92.37 ± 10.71	93.25 ± 8.55	98.10 ± 5.89	<0.001
MCH (g/dL)	30.35 ± 2.95	29.65 ± 3.41	27.31 ± 2.96	26.20 ± 3.29	<0.001
MCHC (Pg)	34.80 ± 1.00	30.79 ± 4.06	28.68 ± 3.69	27.30 ± 5.72	<0.001
Blood glucose (mg/dl)	104.13 ± 16.63	107.15 ± 15.90	83.87 ± 13.16	75.00 ± 4.33	<0.001
Serum protein (g/dl)	69.76 ± 3.03	69.63 ± 2.84	66.69 ± 3.12	65.97 ± 1.15	<0.001
AST (U/L)	23.86 ± 2.22	24.28 ± 2.11	25.96 ± 1.82	27.43 ± 1.15	<0.001
ALT (U/L)	21.15 ± 2.27	22.30 ± 5.37	23.45 ± 2.32	24.93 ± 64	0.005
Total cholesterol (mg/dl)	166.47 ± 18.43	151.33 ± 9.06	144.15 ± 8.46	143.00 ± 5.00	<0.001