|
| Author | Year | Dose and duration | Initial efficacy (at the end of treatment) | Final efficacy (at the end of 6 months) |
|
| Hassan et al. [18] | 1995 | 15 mg/kg im daily for 4 wks. | 14/14 (100%) | Not assessed; however, there were no relapses in 1-year follow-up. |
| Hailu et al. [16] | 2010 | 15 mg/kb body wt. im for 21 days | 67.4% (Um el Kher, Sudan = 33.3%, Kassab, Sudan = 60%, Kenya = 86.7%, Gondar, Ethiopia = 66.7%, Arba Minch, Ethiopia = 96.7%) ( value < 0.001) | 63.8% (Um el Kher, Sudan = 14.3%, Kassab, Sudan = 46.7%, Kenya = 80%, Gondar, Ethiopia = 75%, Arba Minch, Ethiopia = 96.6%) ( value < 0.001) |
| Jamil et al. [19] | 2015 | 11 mg/kg BW im once daily for 21 days | 98.3% | 94.2% |
| Jha et al. [20] | 1998 | 12, 16, or 20 mg/kg/day for 21 days | 12 mg/kg/day group = 90%, 16 mg/kg/day group = 93.3%, 20 mg/kg/day group = 90% | 12 mg/kg/day = 77% (n = 23), 16 mg/kg/day = 93% (n = 28), 20 mg/kg/day = 97% (n = 29) |
| Musa et al. [21] | 2010 | 20 mg/kg/day for 21 days, 15 mg/kg/day for 28 days | 20 mg/kg/day group = 85.7% (95% CI), 15 mg/kg/day group = 90.5% (95% CI) | 20 mg/kg/day group = 80% (95% CI), 15 mg/kg/day group = 81% (95% CI) |
| Sinha et al. [22] | 2011 | 11 mg/kg/day for 21 days | 99.6% (95% CI) | 94.2% (95% CI) |
| Sundar et al. [1] | 2007 | 11 mg/kg/day for 21 days | 98.6% | 94.6% |
| Sundar et al. [23] | 2009 | Group A = 11 mg/kg/day for 14 days (n = 217); group B = 11 mg/kg/day for 21 days (n = 112) | Group A = 91.2%, group B = 96.4% | Group A = 82%, group B = 92% |
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