The Potential Role of Gymnema inodorum Leaf Extract Treatment in Hematological Parameters in Mice Infected with Plasmodium berghei

Figure 1

Effect of GIE on hematological alteration of RBC in PbANKA-infected mice. Groups of mice were infected intraperitoneally with 1 × 10⁷ parasitized RBC of PbANKA and treated orally with 100, 250, and 500 mg/kg of GIE for 4 consecutive days. Hematological parameters of RBC were measured: (a) RBC count, (b) Hb, (c) Hct, (d) MCV, (e) MCH, (f) MCHC, (g) RDW, and (h) reticulocyte. H: healthy mice; UN: untreated mice; GI100, GI250, and GI500: 100, 250, and 500 mg/kg of GIE-treated mice, respectively; CQ: 10 mg/kg of CQ-treated mice. , , and , compared with H. , , and , compared with UN. Results were presented as mean + SEM.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)